Services
Manufacturing
Solutions
The foundation of our business is “The Hearth”, a 175,000 ft2 custom-designed, cGMP facility, dedicated to AAV viral vector manufacturing. We offer end-to-end manufacturing and development services to accelerate gene therapy programs from preclinical stage through clinical, and on to commercial manufacturing.
Request InformationServices
Research & Development Capabilites
- Experienced team able to support early-stage CMC or regulatory strategy
- Affordable small-scale AAV productions for research use using Blaze Vector™
Process Development & Analytical Development
- Experienced team able to support process development and scale up
- End-to-end capabilities from research to GMP grade, reducing the need for bridging studies
cGMP
Manufacturing
- Fully disposable, closed system processing
- Flexible scheduling and maximization of capacity
- Consistent process and product flow for reduction of variation
1-50L research & toxicology
50-500L cGMP
Forge Biologics Cell Line & Ad Helper Plasmid
Ignition Cells™
- Suspension HEK293 mammalian cell line
- Clonal cell line with clear, well documented history for clinical to commercial use
- Optimized for robust transient transfection
- Animal-component free suspension growth
- Scalable production
pEMBR™
- Custom designed rep/cap and Ad helper plasmids
- Improved safety profile
- Forge-specific intellectual property
- Available for pipeline use