Focus

Manufacturing
Solutions

The foundation of our business is “The Hearth”, a 175,000 ft2 custom-designed, cGMP facility, dedicated to AAV viral vector manufacturing. We offer end-to-end manufacturing and development services to accelerate gene therapy programs from preclinical stage through clinical, and on to commercial manufacturing.

Proprietary IgnitionTM Cells
  • HEK293 serum free suspension system
  • Open Licensing and royalty-free usage
  • Developed for yield and consistency
Research and Development Capabilities
  • Experienced team able to support process development and scale up
  • End-to-end capabilities from research to GMP grade, reducing the need for bridging studies
  • 1L-50L research and toxicology grade production available Q3 2020
GMP Manufacturing
  • Fully disposable, closed system processing
  • 50L-500L GMP grade production in 2021
  • Flexible scheduling and maximization of capacity
  • Consistent process and product flow for reduction of variation
Facility
  • Building a state of the art, custom 175,000 ft2 office and production facility
  • cGMP compliant facility designed for EU/US use
Focus

Pipeline

Forge is developing innovative gene therapies that aim to help patients suffering from devastating rare diseases.